The saturated solubility of 4,4'-methylene-bis-(2-chloroaniline) in some pure solvents involving 1,4-dioxane, methanol, ethanol, N,N-dimethylformamide (DMF), n-propanol, isopropanol, N,N-dimethylacetamide (DMA), n-butanol, water, isobutanol, ethylene glycol (EG), ethyl acetate, and acetonitrile was experimentally achieved at intervals of 5 K via the shake-flask approach at pressure p = 101.2 kPa and temperatures from 283.15 to 328.15 K. Within the temperature range examined, the equilibrium solubility values of 4,4'-methylenebis-(2-chloroaniline) in the mole fraction increased with an increase in the studied temperature. The solubility magnitudes followed the decreasing trend as: DMA > DMF > 1,4-dioxane > ethyl acetate > n-butanol > n-propanol > ethanol > acetonitrile > isopropanol > methanol > isobutanol > EG > water. X-ray power diffraction analysis displayed that there did not exist crystalline change or solvation in the equilibration process of 4,4'-methylene-bis-(2-chloroaniline) dissolved in the studied neat solvents. The interactions of solvent-solute and solvent-solvent molecules were studied through linear solvation energy relationships to illustrate the solubility variation. The 4,4'-methylene-bis-(2-chloroaniline) solubility was correlated by the Wilson model, Apelblat equation, lambda h equation, and NRTL model. The obtained maximum values of root-mean-square and relative average deviations were, correspondingly, 11.73 x 10(-3) and 4.87%. The Apelblat equation gave better correlation outcomes than the other equations/models. Additionally, the mixing properties were derived from the solubility magnitudes applied to the Wilson model.