The use of deep eutectic solvents (DES) as "green" solvents could solve at least some of the environmental problems associated with the chemical and petrochemical industry. This paper investigates the applicability of DES made of choline chloride and propylene glycol in a molar ratio of 1:3 for the removal of sulfur and nitrogen compounds from hydrocarbon mixtures. Extraction experiments were performed in quasi-three-component systems, quasi-seven-component model systems and real fuel systems. All the experiments confirmed better solubility of pyridine (compared to thiophene) and nitrogen compounds (compared to sulfur ones) in the investigated DES, indicating its potential use as a denitrification agent. The basic application physico-chemical properties of the investigated DES were determined. Its applicability in multistage extraction processes was confirmed, its extraction capacity was determined and the ability of its regeneration by evaporation was demonstrated. Liquid-liquid equilibria in investigated quasi-three-component systems were described successfully by UNIQUAC activity coefficient model. (C) 2020 Institution of Chemical Engineers. Published by Elsevier B.V. All rights reserved.