Superatoms are nanometer-sized molecules or particles that form ordered lattices, mimicking their atomic counterparts. Hierarchical assembly of superatoms gives rise to emergent properties in lattices of quantum dots, p-block clusters, and fullerenes. Here, we introduce a family of uranium-oxysulfate cluster anions whose hierarchical assembly in water is controlled by two parameters: acidity and the lanthanide or transition-metal countercation. In acid, larger Ln(III)(Ln = La-Ho) link hexamer (U-6) oxoclusters into body-centered cubic frameworks, while smaller Li-III (Ln = Er-Lu and Y) promote linking of 14 U-6 clusters into hollow superclusters (U-84 superatoms). U-84 assembles into superlattices including cubic-closest packed, body-centered cubic, and interpenetrating networks, bridged by interstitial countercations and U-6 clusters. Divalent transition metals (TM = Mn-II and Zn-II) charge-balance and promote the fusion of 10 U-6 and 10 U monomers into a wheel-shaped cluster (U-70). Dissolution of U-70 in organic media reveals (by small-angle scattering) that differing supramolecular assemblies are accessed, controlled by TMII-linking of U-70 clusters. Magnetic measurements of these assemblies reveal Curie-Weiss behavior at high temperatures, without pairing of the 5f(-)(2)electronsdown to 2 K.