In this work, the vapor pressure of binary mixtures of 2-butanol + diethyl carbonate and tert-butanol + diethyl carbonate was measured in the temperature range from 303.15 to 323.15 K. The experimental apparatus used in this work was a simple quasi-static ebulliometer developed in our previous works. The reliability of this apparatus was verified by comparing the measured vapor pressures of 2-butanveol, tert-butanol, and diethyl carbonate with literature data. The comparisons showed that the vapor pressures of pure 2-butanol, tert-butanol, and diethyl carbonate were in good agreement with the literature data with average absolute deviations of 0.6, 0.6, and 0.8%, respectively. The experimental results show that the vapor pressures increased with the alcohol mole fraction for all systems studied. The experimental data were well-correlated with the Wilson, nonrandom two-liquid, and universal quasi-chemical activity coefficient models, giving an average absolute deviation of no more than 1.9%. The binary vapor-liquid equilibrium data obtained in this work showed a positive deviation from Raoult's law.