A pragmatic and swift method for the synthesis of Benzo[a]pyrano[2,3-c]phenazine derivatives via one pot, multicomponent strategy by employing beta-cyclodextrin in EtOH:H2O (1:1) solvent at 70 degrees C has been documented here. Utilization of supramolecular catalyst beta-cyclodextrin which is highly efficient, green, biodegradable and reusable catalyst augments the synthesis amazingly, is the key feature of the current pathway. The catalyst could be recovered for four successive cycles without significant loss in catalytic activity. Graphic