Crude extracts were extracted from blossoms of Citrus aurantium L. var. amara Engl. with 50% ethanol (CAVAP-E), 50% methanol (CAVAP-M), and hot water (CAVAP-W). CAVAP-W had the highest polyphenol yield of 3.7%. The optimum values of liquid/solid ratio, ultrasonic time, and ultrasonic power were 34.06 mL/g, 1 h, and 81.04 W, respectively. The adsorption characteristics of polyphenols were investigated using different macroporous resins. AB-8 and HP-20 resins offered higher adsorption and desorption capacities. Langmuir equation was more suitable to predict the adsorption of polyphenols. The pseudo second-order model was satisfactory to describe the kinetic data of polyphenols onto AB-8 and HP-20.