Exploration of rare-earth (RE)-based Kagome lattice magnets with spin-orbital entangled j(eff) = 1/2 moments will provide a new platform for investigating the exotic magnetic phases. Here, we report a new family of RE3BWO9 (RE = Pr,Nd,Gd -Ho) boratotungstates with magnetic RE3+ ions arranged on Kagome lattice and perform its structure and magnetic characterizations. These serial compounds crystallize in a hexagonal coordinated structure with space group P6(3) (no. 173), where magnetic RE3+ ions have distorted Kagome lattice connections within the ab plane and stacked in an AB-type fashion along the c axis. The interlayer RE-RE separation is comparable with that of the intralayer distance, forming 3-dimensional (3D) exchange coupled magnetic framework of RV' ions. The magnetic susceptibility data of RE3+ BWO9 (RE = Pr, Nd, Gd-Ho) reveal dominant antiferromagnetic interactions between magnetic RE3+ ions, but without visible magnetic ordering down to 2 K. The magnetization analyses for different RE3+ ions show diverse anisotropic behaviors, making RE3+ BWO9 as an appealing Kagome-lattice antiferromagnet to explore exotic magnetic phases.