NMR shows strong analytical capability for obtaining molecular information on materials and is used in a variety of fields. Micro-NMR (mu NMR) is mainly based on low-field NMR (LF-NMR), which makes NMR detection portable and inexpensive. Point-of-care testing (POCT) has gradually become an area of major concern, and scientists have made much progress in applying mu NMR systems for POCT. To the best of our knowledge, this is the first review of the latest development in miniaturization of mu NMR systems. Then, we discuss cutting-edge mu NMR-based applications in POCT and the outlook for future developments.