Green and economical method has been reported for the synthesis of benzylpyrazolyl naphthoquinone and pyrazolo pyranopyrimidines in water at room temperature by using beta-CD-SO3H. beta-Cyclodextrin supported sulfonic acid was prepared by simple one step procedure and characterized by FT-IR spectrum, H-1 NMR, C-13 NMR spectra, TGA, EDAX, XRD, BET surface area analysis and acid-base titration. The present protocol is environmental benign due to heterogeneous reusable catalyst and green reaction medium. This methodology provides excellent yield of the desired product with short reaction time at room temperature, easy workup procedure and no need of column chromatographic separation. Pyrazolyl derivatives are of much importance because this fragment is a key moiety in numerous biologically active compounds. [GRAPHICS] .