혈관내 풍선 확장에 의한 대동맥 차단소생술이 적용된 돼지 복부 장기 조직의 기계적 거동 평가

왕일재; 유지훈; 허업; 송승환; 안효영; 송찬희; 이치승; 유동만; Il Jae Wang; Ji-Hun You; Up Huh; Seunghwan Song; Aorta; Chan-Hee Song; Chi-Seung Lee; Dong-Man Ryu

Korean Journal of Materials Research, Vol.30, No.4, 197-203, April, 2020

DOI10.3740/MRSK.2020.30.4.197 Export Citation

혈관내 풍선 확장에 의한 대동맥 차단소생술이 적용된 돼지 복부 장기 조직의 기계적 거동 평가

Mechanical Behavior of Porcine Abdominal Organ Tissue with Resuscitative Endovascular Balloon Occlusion of the Aorta

왕일재^{1, 2}, 유지훈³, 허업^{2, 4}, 송승환^{2, 4}, 안효영^{2, 4}, 송찬희³, 이치승^{2, 5}, 유동만^{2, 6, †}

¹부산대학교병원 응급의학과
²부산대학교병원 의생명연구원
³부산대학교 대학원 의공학전공
⁴부산대학교병원 흉부외과
⁵부산대학교 의과대학 융합의학교실
⁶미시간주립대학교 기계공학과

Il Jae Wang^{1, 2}, Ji-Hun You³, Up Huh^{2, 4}, Seunghwan Song^{2, 4}, Aorta^{2, 4}, Chan-Hee Song³, Chi-Seung Lee^{2, 5}, and Dong-Man Ryu^{2, 6, †}

¹Dept. of Emergency Medicine, Pusan Nat’l Univ. Hospital, Busan, 49241, Republic of Korea
²Biomedical Research Institute, Pusan Nat’l Univ. Hospital, Busan, 49241, Republic of Korea
³Dept. of Biomedical Engineering, Graduate School, Graduate School, Pusan Nat’l Univ, Busan, 49241, Republic of Korea
⁴Dept. of Thoracic and Cardiovascular Surgery, Pusan Nat’l Univ. Hospital, Busan, 49241, Republic of Korea
⁵Dept. of Convergence Medicine, School of Medicine, Pusan Nat’l Univ, Busan, 49241, Republic of Korea
⁶Dept. of Mechanical Engineering, Michigan State Univ. East Lansing, MI, 48824, USA

E-mail:

Abdominal organs are the most vulnerable body parts under vehicle trauma, and there is high mortality from acute injuries in accidents. There are various ways to reduce this high mortality; one method is Resuscitative Endovascular Balloon Occlusion of the Aorta, which has recently become very popular as a minimally invasive alternative in the emergent management of patients with non-compressible hemorrhages below the diaphragm. However, high safety factor for patients is applied in actual clinical practice because there is no exact standard for the operating time. Therefore, in this study, the effects of the mechanical behavior of organ tissues for the duodenum, kidney, and liver on the operating time of Resuscitative Endovascular Balloon Occlusion of the Aorta is investigated in order to obtain data needed to establish standards of operating time. In characteristic analysis of organ tissues, uniaxial tensile test and compression test are conducted according to the operating time.

Keywords:uniaxial tensile test;compression test;soft tissue;resuscitative endovascular balloon occlusion of the aorta

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[1] Gad MA, Saber A, Farrag S, Shams ME, Ellabban GM, N. Am. J. Med. Sci., 4, 129 (2012)

[2] Singh R, Singh HK, Gupta SC, Kumar Y, Indian J. Community Med., 39, 30 (2014)

[3] Umale S, Deck C, Bourdet N, Dhumane P, Soler L, Marescaux J, Willinger R, J. Mech. Behav. Biomed. Mater., 17, 22 (2013)

[4] Osborn LA, Brenner ML, Prater SJ, Moore LJ, Open Access Emerg. Med., 11, 29 (2019)

[5] Qasim Z, Brenner M, Menaker J, Scalea T, Resuscitation, 96, 275 (2015)

[6] Morrison JJ, Percival TJ, Markov NP, Villamaria C, Scott DJ, Saches KA, Spencer JR, Rasmussen TE, J. Surg. Res., 177, 341 (2012)

[7] Okada A, Nakamoto O, Komori M, Arimoto H, Rinka H, Nakamura H, Clin. Case. Rep., 5, 1565 (2017)

[8] ER-REBOATM Catheter. Prytime medical and the REBOA Company Home Page On the Web. Retrieved March 03, 2010 from https://prytimemedical.com/.

[9] Akhtar R, Sherratt MJ, Cruickshank JK, Derby B, Mater. Today, 14, 96 (2011)

[10] Reik K, Klatt D, Nuzha H, Mueller S, Neumann U, Sack I, Braun J, J. Biomech., 44, 1380 (2011)

[11] Gao Z, Lister K, Desai JP, Ann. Biomed. Eng., 38, 505 (2010)

[12] Roan E, Vemaganti K, J. Biomech. Eng., 129, 450 (2007)

[13] Forsell C, Swedenborg J, Roy J, Gasser TC, Ann. Biomed. Eng., 41, 1554 (2013)

[14] Pierce DM, Maier F, Weisbecker H, Viertler C, Verbrugghe P, Famaey N, Fourneau I, Herijgers P, Holzapfel GA, J. Mech. Behav. Biomed. Mater., 41, 92 (2015)

[15] Raghavan ML, Webster MW, Vorp DA, Ann. Biomed. Eng., 24, 573 (1996)

[16] Wang DH, Makaroun M, Webster MW, Vorp DA, J. Biomech. Eng., 123, 536 (2001)

[17] Manly DA, Boles J, Mackman N, Annu. Rev. Physiol., 17, 515 (2011)

[18] Ambrose JA, Weinrauch M, Arch. Intern. Med., 156, 1382 (1996)

[19] Hmoud B, Singal AK, Kamath PS, J. Clin. Exp. Hepatol., 4, 257 (2014)

[20] Lee YU, Lee AY, Humphrey JD, Rausch MK, Biorheology, 52, 235 (2015)

[21] Preston RA, Epstein M, J. Hypertens., 15, 1365 (1997)

[22] Kleinman RE, et al., Walker’s Pediatric Gastrointestinal Disease, 5th ed., p. 751, B. C. Decker, USA (2008).

[23] Montalvo-Jave EE, Escalante-Tattersfield T, Ortega-Salgado JA, Pina E, Geller DA, J. Surg. Res., 147, 153 (2008)