Nanoparticles have high potential as antibacterial agents, owing to their ability to produce reactive oxygen species (ROS). Recent studies have indicated that this ROS generation is highly affected by the modification of band structure by the introduction of various dopant materials into them. Thus, doped nanoparticles have been extensively studied in the recent literature. The types of dopants, synthesis techniques, and experimental parameters have been found to affect the overall electronic structure of the material, leading to varied antibacterial efficiency. This review summarizes some of the prominent dopant nanomaterials, various methods of synthesizing doped nanoparticles used against bacterial cells, and the main factors involved in it. Despite the extensive research on the mechanism of the antibacterial action, it is still poorly understood mainly due to the inherent complexities and dynamics in cell membranes. Some of the major proposed mechanisms of action of each kind of dopant nanomaterial have also been reported in this work, focusing on the bacterial cell structure.