We report elastic integral and differential cross sections for positron collisions with pyrazine (C4H4N2), for energies up to 10 eV. The cross sections were calculated with the Schwinger multichannel method in the static plus polarization approximation. Our computed elastic integral cross section indicates the presence of a Ramsauer-Townsend minimum and a bound state in the A s scattering symmetry. In the absence of results in the literature on collisions of positrons with pyrazine, we compare the present results with results for pyrimidine and benzene molecules available in the literature.