This paper is concerned with the feasibility of melt spinning of polyacrylonitrile (PAN) copolymer (acrylonitrile/methylacrylate 95.6/4.4 mol% ratio) plasticized with water-ethanol (EtOH) mixtures. The melting point and rheological and stability behaviors of PAN/water/ethanol mixture are reported. The objective is to determine whether this mixture is appropriate for allowing the PAN to be melt spun. The melting point results from differential scanning calorimetry show the T-m of PAN/water/ethanol (70/15/15 wt%) mixture can be reduced to 150 degrees C from 300 degrees C. The time-dependent viscosity results showed that this mixture can be processed at 170 degrees C for more than 100 min without degradation. The steady-shear viscosity results indicated the shear-thinning behavior is observed for this mixture at a temperature ranging from 170 degrees C to 190 degrees C. These rheological data are also highly similar to the reference condition and other potential conditions reported in our previous paper, which indicates PAN/water/ ethanol (70/15/15 wt%) at 170 degrees C is a potential condition for PAN melt spinning. The scanning electron microscopy diagrams show the copolymer strand melt extruded from PAN/ water (70/30 wt%) mixture contains many more voids and bubbles than the PAN/water/ethanol (70/15/15 wt%) system. In conclusion, PAN/water/ethanol (70/15/15 wt%) at 170 degrees C is the most benign set condition (i. e. the composition and temperature) for carrying out the PAN melt spinning process.