In this paper, an Integrated Gasification Combined Cycle (IGCC), which uses waste tires as a feedstock, for power, hydrogen and freshwater production is modeled using both EES and Aspen Plus software packages and assessed thermodynamically. During the study, it is found that tire gasification is a viable solution for leftover tire waste in the world. Furthermore, the novel integration of a multi effect desalination plant, driven by the excess heat from the combined cycle, further increases the systems plant efficiency. The hydrogen production to feed rate ratio is found to be 0.154, which is competitive to high-quality coals, such as Illinois No.6, making waste tires an excellent feedstock to produce hydrogen. The net power production output from the combined cycle is 14.5 MW which was driven by the excess thermal energy of the syngas. The water distillate production rate from the forward flow multi-effect desalination plant at the set conditions is found to be 0.99 kg/s. The systems overall energy and exergy efficiencies obtained are 58.9% and 57.4%, respectively. (C) 2019 Hydrogen Energy Publications LLC. Published by Elsevier Ltd. All rights reserved.