Bluff-body turbulent CH4 : H-2 (1 :1 ) flames at 50% (HM1), 75% (HM2) and 91% (HM3) of the blow-off velocity (235 ms(-1)) were studied experimentally by Masri and co-workers and found to exhibit gradually increasing periodic and shear layer instabilities. The latter are coupled with increasing levels of local extinction with subsequent re-ignition further downstream. This study provides a systematic evaluation of the sensitivity of predictions to molecular mixing and scalar dissipation rate closures. The latter include extended forms of the Euclidean Minimum Spanning Tree (EMST) and modified Curl's (MC) models, applicable to premixed turbulent flames via a closure that accounts for local Damkohler number effects (EEMST and EMC), and a conceptually related blended scalar time-scale approach (BEMST and BMC). Computations are performed using a hybrid finite volume (FV) - transported Joint Probability Density Function (JPDF) algorithm featuring stochastic Lagrangian particles, a comprehensive 48-scalar systematically reduced C/H/N/O mechanism, and a second moment method based on the Generalised Langevin Model that provides a partial resolution of the unsteady fluid motion. The sensitivity to solution parameters affecting the temporal resolution is quantified using Fourier transforms of the time histories of velocity and scalar traces. Radial profiles, conditional means and scatter plots are compared to the experimental data along with burning indices based on the conditional mean temperature. Vortex related instabilities similar to 1 kHz in the outer shear layer appear for all closures with EMC showing periodic local extinction and re-ignition in the neck region for HM3 and flame turbules (i.e., discrete pockets of hot gas) separating periodically at frequencies similar to 85 Hz. Results are similar to well-resolved JPDF/LES simulations for HM1. It is shown that the EMC and (E)EMST models essentially enclose the experimental data for HM2 and HM3. For HM3, emissions of NO are controlled by local extinction events that become increasingly sensitive to the molecular mixing closure as blow-off is approached. (C) 2019 The Combustion Institute. Published by Elsevier Inc. All rights reserved.