Environmental concerns have given a great deal of attention for the production of ultra-low-sulfur fuels. The conventional hydrodesulfurization (HDS) process has high operating cost and also encounters difficulty in removing sulfur compound with steric hindrance. Consequently, various research efforts have been made to overcome the limitation of conventional HDS process and exploring the alternative technologies for deep desulfurization. The alternative processes being explored for the production of ultra-low-sulfur content fuel are adsorptive desulfurization (ADS), biodesulfurization (BDS), oxidative desulfurization (ODS), and extractive desulfurization (EDS). The present article provided the comprehensive information on the basic principle, reaction mechanism, workability, advantages, and disadvantages of conventional and alternative technologies. This review article aims to provide valuable insight into the recent advances made in conventional HDS process and alternative techniques. For deep desulfurization of liquid fuels, integration of conventional HDS with an alternative technique is also proposed.