화학공학소재연구정보센터
Przemysl Chemiczny, Vol.98, No.5, 764-766, 2019
Photodynamic activity of the octaiodide salt of magnesium(II) complex of 1,4,8,11,15,18,22,25-octakis[2-(4-N-metylmorpholin-4-ium)ethoxy]phthaloc yanine against Pseudomonas aeruginosa biofilm
Doses of a bacterial suspension (200 mu L, d. 1.10(7) colony forming units in 1 mL) were deposited on substrates (stainless steel, glass, plastic) and incubated on them at 36 degrees C for 24 h to produce biofilms. The biofilms were immersed in solns. of the title compound for 20 min and exposed after bathing to light beam (wavelength 735 nm, power d. 3 mW/cm(2), 20 min). The use of light-activated title compd. resulted in significant redn. of living cells populations on all tested substrates. The biggest changes were obsd. on the glass substrate.