1-Dodecanol with low solubility in water is a potential solvent to extract phenol from wastewater. The liquidliquid equilibrium data of the ternary system (1-dodecanolphenolwater) were measured at 298.15, 313.15, 323.15, 333.15, and 343.15 K under atmospheric pressure. The experimental data were correlated by the nonrandom two liquids (NRTL) and universal quasi-chemical (UNIQUAC) models, and the corresponding binary parameters were obtained. The results show that the two models agree well with experimental values. Comparison of the average values of the root mean squared deviation (RMSD) from both models reveals that the NRTL model is more accurate than the UNIQUAC model. The effect of temperature on the extraction process is discussed, and temperature has little effect on extraction efficiency. The vant Hoff equation is used to correlate the relationship of distribution coefficient to temperature. The enthalpy change of the extraction process was calculated, and the result shows that extraction of phenol from water by 1-dodecanol is an exothermic process.