The aim of this study was to evaluate the repair bond strength of a dimethacrylate-based composite to two hybrid CAD/CAM blocks after different surface treatments. One hunded and twenty specimens were prepared from two different CAD/CAM blocks (Lava Ultimate (L), Cerasmart (C)). After thermal aging, specimens from each group (n=60) were divided into 6 treatment groups (n=10): (1) No treatment (2) Phophoric acid (37%) for 60s, (3) Hydrofluoric acid (8%) for 60s, (4) Sanblasting with 50-mu m aluminium oxide (5) Er,Cr:YSGG laser treatment at 2W and (6) Er,Cr:YSGG laser treatment at 3W. Single Bond Universal was applied on all specimens and a dimethacrylate-based composite (Tetric N-Ceram) was bonded using Teflon tubes. After thermal cycling, shear bond strength (SBS) was tested, and failure modes were evaluated. Two-way ANOVA and independent t-test were used for statistical analysis (p<0.05). The highest SBS values were detected at Er,Cr:YSGG laser treatment groups (3W) (L:22.7MPa, C:22.6MPa). Lowest SBS values were obtained at no surface pretreatment groups followed by phophoric acid treatment groups which were significantly lower than sandblasting, hydrofluoric acid treatment and Er,Cr:YSGG laser treatment groups (p=0.001). The universal adhesive Single Bond Universal had no effect on promoting bond strength to hybrid ceramics alone or with phosphoric acid. Sandblasting, hydrofluoric acid and laser treatment were effective at increasing repair bond strength, for both Lava Ultimate and Cerasmart.