In this study, we propose new polymeric coatings for metallic implants that impart biocompatibility and antibacterial features to such surfaces. The starting material, poly(cyclic carbonate)-polydimethylsiloxane, was prepared from carbon dioxide fixation and then sequentially reacted by aminolysis with an organoaminosilane, affording the formation of an urethanic polydimethylsiloxane-based material. Finally, a hybrid coating was obtained by performing a sol-gel process on the metallic surfaces, catalyzed by phosphotungstic acid. We provide evidence that due to the polydimethylsiloxane segments governing the surface termination, the hybrid coatings show a hydrophobic character. Furthermore, due the presence of phosphotungstic acid in the upper surface, the adhesion of Gram-positive and Gram-negative bacteria is suppressed in 4 h of contact with aqueous bacterial cultures. In addition, the coatings presented a > 70% cytocompatibility besides a low cytotoxicity, making them interesting candidates as biocompatible materials and an alternative to avoiding the biofilm associated with bacterial infections.