We extend our recent (Rastegar, Ahmadi, and Babu 2017) experimental and computational study of the performance of fibrous filters for the removal of large particles from aqueous dispersions by including the effect of flow velocity on the fiber efficiency and residence time. Dispersions of particles in the size range of 35-600 nm and zeta potential range of -50 to 50 mV were considered. The effect of velocity on minimum efficiency and most penetrating particle size was investigated. The Navier-Stokes equations were solved numerically for a single fiber at different inlet velocities using the ANSYS-FLUENT package and the motion of particles was tracked using the Lagrangian analysis including the hydrodynamic drag, lift, gravity, hydrodynamic retardation, Brownian, van der Waals (vdW), and electric double layer (EDL) forces. The hydrodynamic retardation, EDL, and vdW forces were incorporated in the calculations by developing a user-defined function (UDF) that was compiled with the code. Particular attention was given to the effect of velocity on fiber efficiency due to Brownian, EDL, and vdW forces. It was shown that the CFD results are in a good agreement with the efficiencies calculated from the experimental data obtained by filtering aqueous colloidal ceria dispersions of different zeta potentials at different flow rates.