A significant enhancement in the streaming potential (V-s) was obtained in experiments considering the flow of electrolyte over liquid-filled surfaces (LFSs), where the grooves in patterned substrates are filled with electrolyte immiscible oils. Such LFSs yield larger V-s (by a factor of 1.5) compared to superhydrophobic surfaces, with air-filled grooves, and offer tunability of electrokinetic flow. It is shown that the density, viscosity, conductivity, as well as the dielectric constant of the filling oil, in the LFS, determine V-s. Relating a hydrodynamic slip length to the obtained V-s offers insight into flow characteristics, as modulated by the liquid interfaces in the LFS.