A novel Pt-based Beta encapsulated CeO2 yolk-shell catalyst was successfully synthesized via a RF layer in the synthetic process. The CeO2@Pt-Beta catalyst showed high catalytic activity and stability toward the LT-ESR with respect to the reference Pt-Beta, CeO2-Pt-Beta, which benefited from the special yolk-shell structure and the synergistic effect between the CeO2 movable core and Pt metal. The confinement effect of the yolk-shell architecture contributed to the high dispersion of Pt nanoparticles as well as to the accumulation of reactant molecules in the enclosed void space, which ensured the reactants reacted with CeO2 and Pt to achieve a complete reaction.