Catalysts of quaternary composition have been prepared and tested for the Sabatier process. For catalyst syntheses the following techniques have been used: sol-gel methods, wet impregnation and incipient wetness impregnation. The Sabatier reaction was carried out at temperatures between 520 K and 670 K, pressures of 15 bar and 30 bar using a mixture H-2:CO2 of 4:1. Activity screening of the microscale wall catalysts was performed by a custom-built 10-fold parallel gas-flow microreactor setup in sequential operating mode. To analyze the gas phase compositions GC-FID was used.