Synthesis, Characterization, and Fabrication of Hydrophilic Antimicrobial Polymer Thin Film Coatings

Akshatha Nagaraja; Yashoda Malgar Puttaiahgowda; Ananda Kulal; Ajithkumar Manayan Parambil; Thivaharan Varadavenkatesan

Macromolecular Research, Vol.27, No.3, 301-309, March, 2019

DOI10.1007/s13233-019-7040-5 Export Citation

Synthesis, Characterization, and Fabrication of Hydrophilic Antimicrobial Polymer Thin Film Coatings

Akshatha Nagaraja, Yashoda Malgar Puttaiahgowda^†, Ananda Kulal¹, Ajithkumar Manayan Parambil², and Thivaharan Varadavenkatesan³

Department of Chemistry, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal-576104, India
¹Biological Sciences Division, Poornaprajna Institute of Scientific Research, Devanahalli, Bangalore-562110, India
²SAMTEL Centre for Display Technologies, Indian Institute of Technology, Kanpur-208 016, Uttar Pradesh, India
³Department of Biotechnology, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal-576104, India

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An efficient hydrophilic-antimicrobial thin film coating of functionalized polymaliamides for controlling pathogenic microorganisms is reported in this article. The article is enriched with synthesis, characterization and antimicrobial studies of polymaliamides and its thin film. FTIR, 1H NMR, 13C NMR details of the polymaliamidesis explicated,and the thermal properties of the polymer are revealed using TGA, DSC studies and detailed explanation is provided in the article. The activity of the polymer and thin film against Staphylococcus aureus, Escherichia coli, tuberculosis variant bacteria Mycobacterium smegmatis and Candida albicans are also reported ornately. The morphological behavior of film when interacting with the microbes is studies using SEM and AFM studied and presented elaborately.

Keywords:functionalized polymaliamides;thin film coatings;antimicrobial screening;morphology studies

[References]

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Kurapati R, Vaidyanathan M, Raichur AM, RSC Adv., 6, 39852 (2016)
Xue Y, Xiao HN, Zhang Y, Int. J. Mol. Sci., 16(2), 3626 (2015)
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[1] Lagaron JM, Ocio MJ, Lopez-Rubio A, Antimicrobial Polymers, NJ, USA, 2011.

[2] Kurapati R, Vaidyanathan M, Raichur AM, RSC Adv., 6, 39852 (2016)

[3] Xue Y, Xiao HN, Zhang Y, Int. J. Mol. Sci., 16(2), 3626 (2015)

[4] Talbot GH, Bradley J, Edwards JE, Gilbert D, Scheld M, Bartlett JG, Clin. Infect. Dis., 42, 657 (2006)

[5] Siedenbiedel F, Tiller JC, Polymers, 4, 46 (2012)

[6] Majumdar P, Lee E, Gubbins N, Stafslien SJ, Daniels J, Thorson CJ, Chisholm BJ, Polymer, 50(5), 1124 (2009)

[7] Ajithkumar MP, Yashoda MP, Prasannakumar S, Sruth TV, Kumar VBS, J. Macromol. Sci.-Pure Appl. Chem., 54, 480 (2017)

[8] Vijayasekaran S, Chirila TV, Hong Y, Tahija SG, Dalton PD, Constable IJ, McAllister IL, J. Biomater. Sci.-Polym. Ed., 7, 685 (1996)

[9] Ranucci E, Spagnoli G, Sartore L, Bignotti F, Ferruti P, Schiavon O, Caliceti P, Veronese FM, Macromol. Chem. Phys., 196, 763 (1995)

[10] Lee HY, Yu SA, Jeong KH, Kim YJ, Macromol. Res., 15(6), 547 (2007)

[11] Konsulov V, Lyapova A, Petrov G, Eremieva B, Saha P, J. Univ. Chem. Technol. Metall., 43, 297 (2008)

[12] Cowie JMG, Alternating Copolymers, Springer US, Boston, MA, 2013.

[13] Maeda H, Ueda M, Morinaga T, Matsumoto T, J. Med. Chem., 28, 455 (1985)

[14] Popescu I, Suflet DM, Pelin IM, Chitanu GC, Rev. Roum. Chim., 56, 173 (2011)

[15] Jeong JH, Byoun YS, Ko SB, Lee YS, J. Ind. Eng. Chem., 310 (2001).

[16] Temiz A, Togay SO, Sener A, Guven G, Rzaev ZMO, Piskin E, J. Appl. Polym. Sci., 102(6), 5841 (2006)

[17] Karakus G, Marmara Pharm. J., 73 (2015).

[18] Pato J, Azori M, Tudos F, Makromol. Chem, Rapid Commun., 3, 643 (1982)

[19] Sherigara BS, Yashoda MP, J. Phys. Org. Chem., 12, 605 (1999)

[20] Yashoda MP, Sherigara BS, Venkateswaran G, A. Kinetic Study, 41, 7381 (2000).

[21] Ajithkumar MP, Yashoda MP, Prasannakumar S, Iran. Polym. J., 23, 93 (2014)

[22] Yashoda MP, Sherigara BS, Nayak PV, J. Macromol. Sci.-Pure Appl. Chem., 37A, 1487 (2000)

[23] Parambil AM, Puttaiahgowda YM, Shankarappa P, Turkish J. Chem., 36, 397 (2012)

[24] Prashantha K, Pai KVK, Yashoda MPG, Sherigara BS, Turkish J. Chem., 27, 99 (2003)

[25] Veron L, Revol M, Mandrand B, Delair T, J. Appl. Polym. Sci., 81(13), 3327 (2001)

[26] Harikrishna N, Isloor AM, Ananda K, Obaid A, Fun HK, RSC Adv., 5, 43648 (2015)

[27] Garudachari B, Isloor AM, Satyanaraya MN, Ananda K, Fun HK, RSC Adv., 4, 30864 (2014)

[28] Hebbar RS, Isloor AM, Ananda K, Ismail AF, J. Mater. Chem. A, 4, 764 (2016)

[29] Harikrishna N, Isloor AM, Ananda K, Obaid A, Fun HK, New J. Chem., 40, 73 (2016)

[30] Denyer SP, Stewart GSAB, Int. Biodeterior. Biodegrad., 41, 261 (1998)

[31] Denyer SP, Int. Biodeterior. Biodegrad., 36, 227 (1995)

[32] Nonaka T, Uemura Y, Ohse K, Jyono K, Kurihara S, J. Appl. Polym. Sci., 66(8), 1621 (1997)

[33] Neethirajan S, Dicicco M, Appl. Nanosci., 4, 703 (2014)

[34] Singh S, Patel P, Jaiswal S, Prabhune AA, Ramana CV, Prasad BLV, New J. Chem., 33, 646 (2009)

[35] Li H, Chen Q, Zhao J, Urmila K, Sci. Rep., 5, 1 (2015)