Interdigitated quantum dots, which are multiple stacks of type-I InAs/GaAs quantum dots and type-II GaSb/GaAs quantum dots, are grown using molecular beam epitaxy. By incorporating the interdigitated quantum dots into a p-i-n AlGaAs/GaAs heterojunction solar cell structure, we demonstrate a photovoltaic effect with a 20.6% improvement in open-circuit voltage, when compared to that of another cell incorporating the same quantum dots but with a p-i-n GaAs homojunction architecture. A transmission electron microscopy is performed to analyze strain-induced defects created in the multi-stack quantum dot structures. The heterojunction solar cell incorporating the interdigitated quantum dots realized in this work would find potential applications in high-efficiency single-junction intermediate band solar cells operating under concentrated sunlight.