Over the past decade, remarkable efforts have been made to design low-cost, non-toxic, stable and efficient photocatalyst for water splitting. In the present work, an effective alternative approach to enhance hydrogen production of SrTiO3 was by coupling with MWCNT to form heterojunction followed by doping with Zr4+ ion. The observed type-II band alignment and the polarised electric field could promote the separation of photoexcited charge carriers and photocatalytic activity of these hybrid heterostructures. The theoretical calculation revealed that Zr4+ ion could act as a charge carrier mediator to transfer electrons to the SrTiO3 surface. The MWCNT (6,12,18)/Zr-doped SrTiO3(100) heterostructure exhibited excellent activity due to the combined effect of MWCNT (6,12,18) and Zr-doped SrTiO3(100) monolayers compared with pure SrTiO3. This study offers a novel understanding of designing highly active and stable SrTiO3-based photocatalyst as efficient hydrogen generation material. (C) 2018 Hydrogen Energy Publications LLC. Published by Elsevier Ltd. All rights reserved.