The particle mixingwas studied in a cylindrical stirred tankwith elliptical dished bottomby experiments and simulations. The impeller types used were double helical ribbon (HR) + bottom HR, pitched blade ribbon + bottom HR, inner and outer HR + bottom HR, and pitched blade ribbon + Pfaudler + bottom HR labeled as impellers I to IV, respectively. The quantitative correlations among the rotational speed, fill level and power consumption for impeller I and impeller II were obtained by experiments to validate the discrete element method (DEM) simulations. The particle mixing at different operating conditions was simulated via DEM simulations to calculate the mixing index using the Lacey method, which is a statistical method to provide a mathematical understanding of the mixing state in a binary mixture. The simulation results reveal that as the rotational speed increases, the final mixing index increases, and as the fill level increases, the final mixing index decreases. At the same operating conditions, impeller III is the optimal combination, which provides the highest mixing index at the same revolutions. (C) 2017 The Chemical Industry and Engineering Society of China, and Chemical Industry Press. All rights reserved.