Parallel cascade selection molecular dynamics (PaCS-MD) is a conformational sampling method for generating transition paths from a given reactant to a product. PaCS-MD repeats a cycle of short-time MD simulations from initial structures relevant to the conformational transitions. To efficiently perform PaCS-MD, it might be essential to set reasonable parameters in the applications. As a parameter, the friction coefficient is changed to address how the computational efficiency is affected by the surrounding friction.