In this work, efficient membrane-electrode assemblies (MEAs) have been successfully developed through in-situ chemical precipitation for application to water electrolysis for hydrogen-dissolved water production. The MEAs are fabricated by using cost-effective pore-filled proton exchange membranes possessing both low electrical resistances and proper crosslinking properties. The MEA prepared under the optimum conditions shows excellent water electrolysis performance mostly comparable with that of a commercial Nafion-based MEA.