The Mo0.25Co1.257W0.25S3 composite was synthesized using a single-step hydrothermal method and hybridize with graphene oxide as an electrocatalyst for methanol oxidation. The structure and morphology of this composite were validated by using x-ray diffraction, energy dispersive x-ray spectroscopy, field emission scanning electron microscopy (FESEM) and high-resolution transmission electron microscopy (HRTEM). Cyclic voltam-metry (CV) and electrochemical impedance spectroscopy (EIS) was applied to survey the operation of modified glassy carbon electrode with the foregoing composite. The results showed suitable electrocatalytic property for the direct methanol fuel cell, as well as a dramatic diffusion current, which was confirmed by the Tafel diagrams.