The design and operation of a new solar photoreactor prototype named Offset Mull Tubular Photoreactor (OMTP) is presented. The OMTP advances over the compound parabolic collector (CPC) photoreactor, which is one of the most efficient design for large-scale solar detoxification of water and wastewater. The OMTP design is based on a simple modification of the common CPC and included a supplementary set of tubes in the space occupied by the axes of intersection of the CPC reflective involutes. This new reactor configuration increased the irradiated reactor volume by 79% and the fluid residence time by up to 1.8-fold in comparison to the CPC, for the same solar irradiated area (footprint). The model parameters used for comparing and scaling the OMPT and CPC were beta (reactor volume/total volume), a (area of absorption/total volume), alpha(g) (physical area/total volume), degradation efficiency eta(alpha) per unit area, and the operating volume. The total solar energy absorbed in the reactors (1.74 m(2) footprint) was 15.17 W for the CPC and 21.86 W for the OMTP, which represents an overall gain of 44% for the latter. The performance of the OMTP and CPC were compared at the same value of solar exposure, beta of 0.3 with optimal photocatalyst loading of 0.25 g/L titanium dioxide (TiO2 P25). The degradation efficiencies of methylene blue, dichloroacetic acid, 4-chlorophenol (120 ppm initial concentration) in the OMTP were up to 81%, 125%, 118% and 242% higher, respectively, in comparison to the CPC after 8000 J/m(2) of accumulated solar energy. The OMTP should outperform the CPC in environmental and renewable energy applications of solar heterogeneous photocatalysis.