The present article demonstrates a simple method for synthesizing the highly stabilized Pd(0) nanoparticles by using supported 12-tungstophosphoric acid as a stabilizer as well as a carrier. The obtained material was characterized by different methods and the presence of nanoparticles on the surface of the carrier was confirmed, especially by TEM and XPS. As an application, the use of material was explored for the well-known fascinating organic transformation, Suzuki-Miyaura cross coupling reaction in aqueous medium as well as in neat H2O. It was found that the material shows an outstanding activity as the heterogeneous catalyst (0.0096mol% of Pd) for both aqueous medium (99% conversion, TOF 96958h(-1)) and in neat H2O (89% conversion, TOF 46390h(-1)) towards biphenyl. The catalyst was recovered by filtration only, regenerated and reused without any significant loss in conversion. Study shows that the present catalyst is truly heterogeneous and sustainable for the said reaction, in either of the medium. The viability of the catalyst was learned toward different substrates and found to be excellent in almost all cases.Graphical AbstractPd nanoparticles stabilized by supported 12-tungstophosphoric acid is proved to be sustainable and excellent for Suzuki-Miyaura reaction with very high catalyst to substrate ratio as well as TOF. [GRAPHICS] .