In this study we have synthesized a new class of compounds incorporating of chalcones and laterally substituted fluoro group. A series of new chalcones with five aromatic rings is synthesized and characterised by elemental analyses and spectroscopic techniques such as Fourier transform infrared [FT-IR] and proton magnetic resonance magnetic resonance [H-1 NMR] spectroscopy. The mesomorphic properties of these compounds were observed by optical polarized light microscopy (POM) and confirmed by differential scanning calorimetry (DSC). It is found that all the prepared materials display enantiotropic LCs phases except first three homologue in present series. The lower homologues (n = 4 to 12) display SmC and nematic phase while, in higher homologues (n = 14 to 18) only SmC phase were seen in heating and cooling condition. [GRAPHICS] .