Nowadays, organic donor-acceptor molecules have attracted a lot of scientific attention because of their unique properties and potential applications in various fields. Although tetrathiafulvalene-tetracyanoquinodimethane (TTF-TCNQ) is well known charge transfer salt for a long time, the first application of this material as ion-to-electron transducer in ion-selective electrodes is presented. As a proof of concept, potassium-selective and nitrate-selective solid-state electrodes were constructed. Moreover, TTF-TCNQ intermediate layers were fabricated using two organic solvents. Developed potassium sensors displayed a good Nernstian response with a slope of 58.52 mV/decade (10(-6)-10(-1) M K+), whereas the nitrate-selective electrodes showed a sensitivity of -58.47 mV/decade (10(-5)-10(-1) M NO3-). Reproducible standard potentials and low detection limits were observed. Potential stability of studied electrodes was evaluated using current-reversal chronopotentiometry. The capacitance of TTF-TCNQ-contacted electrodes is 255 mu F and 629 mu F for K+ and NO3- sensors. The results of measurements conducted reveal that TTF-TCNQ has an appropriate effect on potentiometric sensors performance. (C) 2018 The Electrochemical Society.