Rate coefficients for methoxybenzene, 1,2,3-trimethoxybenzene, 1,2,4-trimethoxybenzene and 1,3,5-trimethoxybenzene reacting with hydroxyl radicals have been studied in a 1080 L chamber at atmospheric conditions using the relative kinetic method. The following rate coefficients (cm(3) molecules(-1) s(-1) ) were determined at (298 +/- 2) K: (2.86 +/- 0.12) x 10(-11) for methoxybenzene, (7.70 +/- 0.36) x 10(-11) for 1,2,3-trimethoxybenzene, (1.29 +/- 0.56) x 10(-10) for 1,2,4-trimethoxybenzene and (1.56 +/- 0.69) x 10(-10) for 1,3,5-trimethoxybenzene. This work constitutes the first kinetic study for the three isomers of trimethoxybenzene. Differences in reactivity are discussed. Atmospheric lifetimes and implications are presented. (C) 2018 Elsevier B.V. All rights reserved.