This paper reports the controlled release of citrus unshiu extract from spherical silica hybrid liposome (silicified liposomes) particles. Silicified liposome particles were synthesized by silicification through the sol-gel reaction with TEOS as a silica source of the hydrophilic region of lecithin. In addition, we achieved the various characterization analyses such as SEM-EDS, DLS, FT-IR, and TGA, respectively. The silicified liposomes particles effectively entrapped as much as 314.2 mg/L solution of the citrus unshiu peel extract After the citrus unshiu peel extract was entrapped in the silicified liposomes, the controlled release profile was investigated and the results showed that the maximum release was 41.4%. The release kinetics were fitted to various kinetic models, such as pseudo-first, pseudo-second-order kinetic and intraparticle diffusion models. The pseudo-second-order kinetic model showed good matching with the experimental release results. Furthermore, the antioxidant activity of citrus unshiu peel extract was measured by the DPPH free radical scavenging method. (C) 2018 Elsevier B.V. All rights reserved.