Journal of Physical Chemistry B, Vol.104, No.5, 913-917, 2000
A light scattering theory applicable to ions which aggregate in solution and possess two charge centers of one sign and one charge center of the opposite sign: Aggregation of BTA-243 in an aqueous medium
In a slightly acidic aqueous medium, the drug BTA-243 produces ions which aggregate in a manner similar to that shown by surfactant ions. Each of these ions has a positive charge center and two negative charge centers. A new procedure developed to handle light scattering data collected from this unique system indicates that in a 0.2 M sodium acetate buffer, the drug has an aggregation number between 80 and 105.