TiO2 nanoflowers modified with MoS2 and GO nanosheets are prepared by a one-step hydrothermal method followed by a dip-coating process. The morphology, structure and composition of the samples are investigated by XRD, SEM and XPS, respectively. The photoelectrochemical (PEC) measurement reveals that the modified samples exhibit obvious improved photocurrent density. The enhancement can be attributed to the higher absorption in visible light region and faster charge transmission as analyzed by the UV-Vis absorption, photoluminescence spectra and electrochemical impedance analysis. This facile method provides a promising low-cost way to enhance the PEC performance of TiO2-based photoanodes.