LiNi0.5Co0.2Mn0.3O2 (T-NCM) cathode material with hollow microsphere structure is synthesized by binary template method. The microspheres with diameters of about 2.5 mu m and hollow interior structure with walls thickness of approximately 0.8 mu m. When tested by half-cells, T-NCM material exhibits better electrochemical performances than LiNi0.5Co0.2Mn0.3O2 (C-NCM) material prepared by co-precipitation method. Specifically, T-NCM sample delivers discharge capacities of 180.3, 148.5 and 127.8 mAh g(-1) at 0.2C, 5C and 10C rates between 3.0 and 4.3 V, respectively. After 100 cycles, capacity retention ratios at 0.2C and 5C are 86.58% and 82.63%, respectively. In addition, application property of the as-synthesized materials is evaluated by the fabrication of 18650 full batteries. The 18650 battery assembled with T-NCM material as the cathode achieves discharge capacities of 2138.8, 1870.2, and 1652.2 mAh at 0.5C, 5C and 10C rates under the voltage range of 2.75-4.2 V, respectively, with capacity retention rate maintained as high as 96.30% after 500 cycles at current of 2 A (1C), which are superior to that of 18650 battery fabricated with C-NCM as the cathode. The better processability of T-NCM is ascribed to the more uniform particle size distribution and smaller particle size. The excellent electrochemical performances of T-NCM electrode in half-cells and 18650 full batteries can be attributed to the unique hollow microspheres structure. This work illustrates that the T-NCM material is a promising candidate as cathode material for power lithium ion batteries.