A poly(styrenesulfonic acid)-carboxymethylcellulose (PSSA-CMC) blend catalytic membrane was prepared for ethyl lactate production in a pervaporation-aided membrane reactor. The effects of PSSA/CMC concentration, initial molar ratio, and temperature on acid conversion were evaluated. Additionally, the separation performance of membrane was investigated as a function of flux and separation factor. Increasing the temperature enhanced lactic acid conversion at constant alcohol:acid ratio.