The enhancement of convective heat transfer in single-phase heat transfer through the use of helicoidally corrugated tubes has been studied numerically. By comparing the large eddy simulation (LES) results with detailed Stereo-PIV and Liquid Crystal Thermography measurements obtained at the von Karman Institute for Fluid Dynamics (VKI), a validated numerical framework was obtained. Heat transfer enhancements of 83-119% were seen, at the cost of pressure losses that were approximately 5.6 to 6.7 times higher than for a bare tube. To extrapolate the results to industrial Reynolds numbers at which experimental data is scarce, the simulation data was used to develop an improved near-wall Reynolds stress transport model (RSTM) that more accurately describes the heat flux vector. Comparison of both global and local flow characteristics at different Reynolds numbers confirms that the approach allows more accurate predictions over a wider range of design and operating parameters than using two-equation turbulence models, while the computational cost is still significantly lower than LES. (C) 2017 American Institute of Chemical Engineers