화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Macromolecular Research, Vol.26, No.3, 263-269, March, 2018
DOI10.1007/s13233-018-6035-y  Export Citation
Protein-Patterning on Functionalized, Non-Biofouling Poly[N-acryloxysuccinimide-co-oligo(ethylene glycol) methyl ether methacrylate] Film-Coated PET Surfaces
Gyeongyeop Han, Yoonyoung Kim1, Kyungtae Kang1, Bong Soo Lee2, †, and Jungkyu K. Lee†
  • Department of Chemistry and Green-Nano Materials Research Center, Kyungpook National University, Daegu 41566, Korea
  • 1Department of Applied Chemistry, Kyung Hee University, Gyeonggi 17104, Korea
  • 2Center for Cell-Encapsulation Research, Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea
E-mail:,
We successfully fabricated poly(ethylene terephthalate) (PET) surfaces through a perfluoroaryl azide-based photochemical reaction, and subsequently formed an intrinsically activated, non-biofouling poly[N-acryloxysuccinimide-co-oligo(ethylene glycol) methyl ether methacrylate] on the surface through surface-initiated, controlled radical polymerization. The grafted copolymer film on PET facilely generated a protein pattern using a microcontact printing technique without employing both an activation step to introduce an active functional group (e.g., succinimidyl ester) and a passivation process for minimizing non-specific adsorption. Consequently, we characterized the functionalized PET surfaces by using various methods including contact angle measurement, X-ray photoelectron spectroscopy (XPS), scanning probe microscopy (SPM), field-emission scanning electron microscopy (FE-SEM). In addition, we evaluated the non-biofouling efficacy of the protein-patterned copolymer film on PET by confocal laser scanning microscopy.
Keywords:organic polymer substrate;copolymer coating;biopatterning;surface-initiated controlled radical polymerization;photochemical reaction
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