Porous alpha-Fe2O3 nanoparticles are directly grown on acid treated carbon cloth (ACC) using a simple hydrothermal method (denoted as ACC-alpha-Fe2O3) for employment as a flexible and wearable electrochemical electrode. The catalytic activity of ACC-alpha-Fe2O3 allowing the detection of dopamine (DA) is systematically investigated. The results showed that the ACC-alpha-Fe2O3 electrode exhibits impressive electrochemical sensitivity, stability and selectivity for the detection of DA. The detection limit determined with the amperometric method appears to be around 50 nM with a linear range of 0.074-113 mu M. The impressive DA sensing ability of the as prepared ACC-alpha-Fe2O3 electrode is due to the good electrochemical behavior and high electroactive surface area (19.96 cm(2)) of alpha-Fe2O3 nanoparticles anchored on the highly conductive ACC. It is worth noting that such remarkable sensing properties can be maintained even when the electrode is in a folded configuration. (C) 2017 Elsevier B.V. All rights reserved.