In this study, comparison and effect of Cinder supported with Lanthanum and Manganese oxide as catalyst for transesterification of triglyceride to methyl ester is proposed. The reaction mechanism along with the effects of methanol to oil molar ratio, amount of catalyst to oil, reaction temperature were also discussed. Moreover reusability of catalyst, catalyst resistance toward Free Fatty Acid and water were also discussed. The results show that yield of biodiesel produced with Mn:La:Cinder catalyst was 99% at >= 150 degrees C in 6 h. Cinder supported with Mn shows conversion of triglycerides from soybean oil in reaction with methanol after 6 h was over 99% at 150 degrees C. For both catalyst 3wt% of catalyst based on oil, 24:1 methanol/oil molar ratio was reused for 7 times with regeneration. The catalysts displayed great resistance toward 2.5% water and 1% wt fatty acids. (C) 2017 Hydrogen Energy Publications LLC. Published by Elsevier Ltd. All rights reserved.