Based on the characteristics of water injection into the reservoir and using the streamline calculation method and the unit analysis method, we derive a computational model for non-Darcy seepage production from a rhombus reverse five-point well pattern in a low-permeability reservoir. In order to test the adequacy of the method, we used data on fluid seepage from a real low-permeability reservoir. The method identified a relationship between the startup pressure gradient, the hole spacing, the row spacing, and the production capacity, and also provided a basis for designing a model for a rhombus injection well pattern in low- permeability reservoirs.