This article presents a mathematical model for studying peristaltic mechanism of combine pressure and electro-osmotically driven flow of ionic liquids through a micro-channel having electrokinetic effects. The velocity slip and the thermal slip conditions at the channel wall are taken into account for investigating the thermomechanical interactions. The micro-channel is assumed to have porous structure. The governing equations for fluid flow and heat transfer in the electrical double layer (EDL) together with the Poisson-Boltzmann equation are considered. The analytical solutions have been obtained under low Reynolds number and long wave length assumptions. It is also assumed that the channel height is much greater than the thickness of the electrical double layer (EDL). The essential features of electroosmotically driven flow and associated heat transfer characteristics in a micro-channel are clearly demonstrated by varying dimensionless parameters for velocity profile, temperature profile, pressure distribution, stream function, wall shear stress and the Nusselt number. The pressure drop exhibits a linear dependence on the flow rate. The study reveals that the electro-osmotic parameter has an enhancing effect on the size of the trapping bolus while the reducing effect on porous permeability of the channel. The temperature distribution is significantly influenced by Joule heating parameter and Brinkman number. The study bears the potential applications in biomedical engineering for the development of microfluidic devices in particular microfluidic pump to transport small volume of ionic liquids by maintaining temperature distribution. (C) 2017 Elsevier Ltd. All rights reserved.