The effect of Ni, Fe and Mn in different proportions on microstructure and pollutant-catalyzed properties of Ni-Fe-Mn-O negative temperature coefficient ceramic nanocompositions was studied. Structural and physical characterization of all the samples was carried out by using X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Brunauer Emmett Teller (BET) method, Fourier transform infrared spectroscopy (FT-IR), Raman spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM) and thermogravimetric (TG). The results revealed that the interplanar spacing decreased with increasing Fe content, the grain size decreased with increasing Ni content, the substitution of Ni2+ in the tetrahedral sites by Fe2+ increased with increasing Fe content. And increase of iron could improve Ni-Fe-Mn-O high temperature stability. The low-temperature thermal removal efficiencies of 30 mg/L methyl orange solution for NiFeMnO4, Ni0.6Fe0.9Mn1.5O4, Ni0.6Fe1.5Mn0.6O4 and Ni0.3Fe2.1Mn0.6O4 systems were 83.8%, 75.2%, 78.5% and 60.3% at 2400 min, respectively. And the microwave combining with H2O2 removal efficiencies of 30 mg/L methyl orange solution for NiFeMnO4, Ni0.6Fe0.9Mn1.5O4, Ni0.6Fe1.5Mn0.6O4 and Ni0.3Fe2.1Mn0.6O4 systems were 96.5%,93.8%, 98.7% and 98% at 6.0 min, respectively. These results indicated that the Ni-Fe-Mn-O ceramics with appropriate increase of iron were useful for industrial applications on degrading organic pollute. (C) 2017 Elsevier B.V. All rights reserved.