The reactions of O(P-3) atoms with furan, 2-methylfuran (2-MF), and 2,5-dimethylfuran (2,5-DMF) were studied at elevated temperatures by using a shock tube technique coupled with atomic resonance absorption spectroscopy (ARAS). The rate coefficients (k) determined from the time profiles of O(P-3) atoms were expressed by the relation of k(O+2,5-DMF) > k(O+2-MF) > k(O+FURAN). The molecular orbital calculations with CBS-QB3 level were also performed and the possible product channels of these reactions were discussed.