Gas-liquid flow is frequently investigated in microreactor research, but mainly focused on well-described Taylor-bubble flow. Dispersed flow featuring small bubbles results in increased specific surface-to volume ratio and more stable flow in microchannels. The influence of local energy dissipation rate and channel geometry was investigated on gas-liquid dispersion in nozzles with hydraulic diameter from 0.25 to 0.5 mm. Resulting bubble diameter and its size distribution were examined. For systems with increased bubble coalescence, micronozzles can be switched in series to redisperse the flow for augmented mass transfer. The contribution will give a fundamental view on bubble generation, redispersion for dispersed gas-liquid systems in microstructured devices together with design and scale-up discussion. (C) 2016 Elsevier Ltd. All rights reserved.